CMC ICOS Biologics – Seattle Manufacturing Capacity Cell Culture Facilities
- cGMP cell banking facility
- Cell culture development labs with:
- 6 x 5L bioreactors (batch, fed-batch, or perfusion)
- 6 x 15L bioreactors (batch/fed batch)
- 3 x 40L bioreactors (batch/fed batch)
- 150L cell culture pilot plant (non-cGMP)
- cGMP manufacturing line with a 1600L production bioreactor
- Seed bioreactors (350L)
- Batch, fed-batch, and continuous perfusion
- Perfusion capacity up to 2000L/day via an external ATF technology
- cGMP manufacturing line with a 3000L production bioreactor
- Seed bioreactors (750L)
- Batch, fed-batch, and continuous operation
The CMC ICOS Biologics Manufacturing plant has been in operation for the production of clinical products since 1997.
A separate building is used to warehouse raw materials, and a cGMP program is in place for shipping and receiving products and raw materials.