Microbial Cell Line Development Services
CMC's Microbial Upstream Development group has extensive experience in establishing, optimizing and characterizing high cell density E. coli and Pichia fed-batch processes. For E. coli suitable expression vectors and host strains are available and the microbial cGMP Cell Banking services are embedded in the development group. The overall focus is to develop high yielding cell lines and processes that are robust and scalable, with high productivity in regulatory friendly media.

E. coli cell line development

• In-house developed expression vectors
• Host strains HMS174 and BL21 available